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Regular consumption of coffee is associated with a reduced risk of primary sclerosing cholangitis (PSC), autoimmune liver disease, according to a study conducted at the Mayo Clinic in the U.S., advances the portal Isaúde. CSF is an inflammatory disease of the bile ducts, which results in inflammation and subsequent fibrosis, which can lead to liver cirrhosis, liver failure and cancer of the bile ducts. "Although rare, PSC has extremely negative effects. We are always looking for ways to reduce risk and demonstrate for the first time a new environmental factor that can also help us determine the cause of this and other autoimmune diseases devastating," says study author Craig Lammert, gastroenterologist at Mayo Clinic. The study analysed a large group of U.S. patients with PSC and primary biliary cirrhosis (PBC) and a group of healthy patients. The data showed that coffee consumption was associated with a reduced risk of CSF, but not PBC. Patients with PSC were much more likely to not drinking coffee than healthy subjects. Patients with PSC also spent nearly 20% less of their time drinking coffee regularly than the control group. "The study suggests that PSC and PBC differ more than originally thought. In the future, we can look at what this discovery tells us about the causes of these diseases and how best to treat them," says the senior author of the research Konstantinos Lazaridis.
Source: Portal de Oncologia Português